Peptide quantitation enables comparison of relative protein abundances across experimental conditions. Our technologies support both untargeted and targeted analyses.
While not an all-inclusive list, several of the most common study types are listed below.
Investigator provides proteins in solution of known composition. Samples are analyzed independently and quantitation is determined by precursor peak area. Mainly used when isotopic labeling strategies are not possible.
Investigator provides proteins in solution of known composition and TMT labeling kit. MS Center will perform enzymatic digestion, TMT labeling, and peptide fractionation prior to MS analysis.
Targeted quantitation of peptides from proteins of interest. Requires custom method development for each protein of interest.