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The Center is well-equipped with state-of-the-art instrumentation to provide a competitive edge for investigators at MCW and partner institutions. 

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Thermo Orbitrap Fusion Lumos with ETD

High resolution and high mass accuracy instrument dedicated to proteomic and glycoproteomic analyses. Operated only by the most experienced experts in the MS Center.

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The Lumos is the most advanced MS instrument currently available.

  • Capable of identification and quantification of peptides, proteins, post-translational modification identification, and top-down fragmentation of intact proteins.
  • Four modes of fragmentation (CID, HCD, ETD, EThcD) support the analysis of a wide range of molecules, including glycopeptides, glycans and modified peptides.
  • Features a 30 Hz Orbitrap and Advanced Peak Detection. Resolving power > 500,000 @ m/z 200.
    Mass accuracy <1 ppm.
    Mass range = 50-6000 m/z.

Thermo LTQ Orbitrap Velos

High resolution and high mass accuracy instrument used for glycan structural analyses. Operated only by the most experienced experts in the MS Center.

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Thermo LTQ XL

Low resolution analysis of small molecules, proteins, and peptides. Equipped with nanoLC for automated injection. Used for QC testing and available for self-service projects. 
 

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Agilent G6538 Q-TOF

Small molecule accurate mass determination, intact protein and simple peptide mass measurements. Available for self-service projects. 

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Agilent G6430 QQQ

Targeted quantitation of metabolites and small molecules.Operated only by the most experienced experts in the MS Center.

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Thermo LTQ

Low resolution analysis of small molecules, proteins, and peptides. Equipped with microflow LC for automated injection. Available for self-service projects. 
 

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Thermo DSQ - Focus GC

GC-MS used for the measurement of volatile organics and lipids. Available for self-service projects. 

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